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Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

2017-08-28

Abstract excerpt

Subcortical brain structures are integral to motion, consciousness, emotions, and learning. We identified common genetic variation related to the volumes of nucleus accumbens, amygdala, brainstem, caudate nucleus, globus pallidus, putamen, and thalamus, using genome-wide association analyses in over 40,000 individuals from CHARGE, ENIGMA and the UK-Biobank. We show that variability in subcortical volumes is herita...

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Literature Corpus work
448bdd24-bb33-5093-ba64-1d7758623504
DOI
10.1101/173831
Open publication

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Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals WorldwideDOI 10.1101/173831
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