Article

Concordance of Genetic Variation that Increases Risk for Tourette Syndrome and that Influences its Underlying Neurocircuitry

2018-07-13

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> There have been considerable recent advances in understanding the genetic architecture of Tourette Syndrome (TS) as well as its underlying neurocircuitry. However, the mechanisms by which genetic variations that increase risk for TS - and its main symptom dimensions - influence relevant brain regions are poorly understood. Here we undertook a genome-wide investigation of the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1e953b6c-263e-519e-bdba-28d9ebff5202
DOI: 10.1101/366294

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Concordance of Genetic Variation that Increases Risk for Tourette Syndrome and that Influences its Underlying NeurocircuitryDOI 10.1101/366294Read

Concordance of genetic variation that increases risk for Tourette Syndrome and that influences its underlying neurocircuitrySemantic proximity Read

Genetics of Tourette Syndrome.Semantic proximity Read

The genetic architecture of the human thalamus and its overlap with ten common brain disorders.Semantic proximity Read

Overlap in genetic risk for cross-disorder vulnerability to mental disorders and genetic risk for altered subcortical brain volumes.Semantic proximity Read

Genome-wide association analysis of the human thalamus identifies novel genomic loci and reveals genetic overlap with distinct cortical regions and ten brain disordersSemantic proximity Read

Genome-wide Association Study identifies two novel loci for Gilles de la Tourette SyndromeSemantic proximity Read

Genome-Wide Association Study Points to Novel Locus for Gilles de la Tourette Syndrome.Semantic proximity Read

Genetics of Tourette syndrome and tic disorders.Semantic proximity Read

Polygenic risk score-based phenome-wide association study identifies novel associations for Tourette syndromeSemantic proximity Read

Polygenic risk score-based phenome-wide association study identifies novel associations for Tourette syndromeSemantic proximity Read

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals WorldwideSemantic proximity Read

Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture.Semantic proximity Read