Article
Thalamocortical Structural Covariation Networks Are Related to Familial Risk for Schizophrenia in the Context of Lower Nuclei Volume Estimates in Patients: An ENIGMA Study.
Biological psychiatry - 1 Nov 2025
Lella Annalisa, Antonucci Linda A, Passiatore Roberta, Bellantuono Loredana, Selvaggi Pierluigi, Popolizio Teresa, Di Sciascio Guido, Saponaro Alessandro, Ricci Patrizia, Altamura Mario, Blasi Giuseppe, Rampino Antonio, Vriend Chris, Calhoun Vince D, Rootes-Murdy Kelly, Goldman Aaron L, Baeza Inmaculada, Castro-Fornieles Josefina, Sugranyes Gisela, De la Serna Elena, Pomarol-Clotet Edith, Fatjó-Vilas Mar, Salvador Raymond, Karuk Andriana, Fuentes-Claramonte Paola, Glahn David C, Rodrigue Amanda L, Blangero John, Wang Lei, Lee Taeyoung, Einenkel Karolin E, Hamers Saskia, Gruber Oliver, Preda Adrian, Chung Young-Chul, Odkhuu Soyolsaikhan, Vallée Corentin, Dazzan Paola, Marcelis Machteld, Michielse Stijn, Brosch Katharina, Stein Frederike, Nenadić Igor, Straube Benjamin, Thomas-Odenthal Florian, Kircher Tilo, Carruthers Sean, Rossell Susan L, Sumner Phillip J, Van Rheenen Tamsyn E, Demro Caroline, Ramsay Ian S, Sponheim Scott R, Lencer Rebekka, Meinert Susanne, Hahn Tim, Dannlowski Udo, Grotegerd Dominik, Ciccarelli Mariateresa, Iasevoli Felice, Pontillo Giuseppe, Pearlson Godfrey D, Cobia Derin, Piras Fabrizio, Banaj Nerisa, Vecchio Daniela, Barendse Marjolein E A, van Haren Neeltje E M, Jo Hang Joon, Sim Kang, Quidé Yann, Green Melissa J, Slate Rachael, Cecere Giacomo, Omlor Wolfgang, Homan Stephanie, Homan Philipp, Thomopoulos Sophia I, Turner Jessica A, van Erp Theo G M, Thompson Paul M, Bertolino Alessandro, Pergola Giulio
Abstract excerpt
BACKGROUND: Structural brain differences in the thalamus and the cortex have been widely reported in schizophrenia (SCZ) relative to neurotypical control individuals (NCs). Most previous studies examined the thalamus as a whole as a single region of interest. In addition, findings in individuals at familial high risk for SCZ (FHRs) remain inconclusive. Here, we investigated whether local and network-wide...
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