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AlzGPS: A Genome-wide Positioning Systems Platform to Catalyze Multi-omics for Alzheimer’s Therapeutic Discovery

2020-09-20

Abstract excerpt

<h4>Background</h4> Over15 million family members and caregivers have expended $220 billion for care of patients with AD and other dementias, and the attrition rate for AD clinical trials (2002-2012) is estimated at 99.6%. While recent DNA/RNA sequencing and other multi-omics technologies have advanced the understanding of the biology and pathophysiology of AD, no effective disease-modifying or preventive therapi...

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Literature Corpus work
4b8e7ebb-2168-54e0-837d-7e518fef4a5f
DOI
10.1101/2020.09.17.302612
Open publication

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