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Integrating genetically predicted transcriptomic signatures with longitudinal real-world data enables scalable drug repurposing for Alzheimer’s disease

2026-05-15

Abstract excerpt

<title>Abstract</title> <p> Drug repurposing offers a potential strategy to expand treatment options for conditions with limited therapies, but advancing repurposing candidates toward clinical implementation remains a challenge. Large-scale data, together with advanced genetic and epidemiological methods, may help address this gap. Here, we present an integrative digital medicine approach that combines genetical...

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Literature Corpus work
e0d2c726-5a71-5456-ab70-5135b362a93c
DOI
10.21203/rs.3.rs-9518587/v1
Open publication

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Integrating genetically predicted transcriptomic signatures with longitudinal real-world data enables scalable drug repurposing for Alzheimer’s diseaseDOI 10.21203/rs.3.rs-9518587/v1
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