Article

A Human Liver Organoid Screening Platform for DILI Risk Prediction

2021-08-28

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background and Aims</h4> Drug-induced liver injury (DILI), both intrinsic and idiosyncratic, causes frequent morbidity, mortality, clinical trial failures and post-approval withdrawal. This suggests an unmet need for improved in vitro models for DILI risk prediction that can account for diverse host genetics and other clinical factors. In this study, we evaluated the utility of human liver...

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Literature Corpus work: 4b7c3259-9722-5bcd-9a48-e31a7d4703a4
DOI: 10.1101/2021.08.26.457824

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