Article
The sum and the parts: dynamics of multiple and individual metastases during adaptive therapy
2022-08-05
Abstract excerpt
Evolutionary therapies, such as adaptive therapy, have shown promise in delaying treatment resistance in late-stage cancers. By alternating between drug applications and drug-free vacations, competition between sensitive and resistant cells can be exploited to maximize the time to progression. However, the optimal schedule of this dosing regimen depends on the properties of the tumor, which often are not directly...
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Identifiers and source
- Literature Corpus work
- 4b36b5d9-2106-56c8-955a-01983f22b12d
- DOI
- 10.1101/2022.08.04.502852