Article

Predicting Treatment Outcomes from Adaptive Therapy — A New Mathematical Biomarker

2025-04-09

Abstract excerpt

Standard-of-care cancer therapy regimens are characterized by continuous treatment at the maximum tolerated dose; however, this approach often fails on metastatic cancers due to the emergence of drug resistance. An evolution-based treatment paradigm known as ‘Adaptive Therapy’ has been proposed to counter this, dynamically adjusting treatment to control, rather than minimize, the tumor burden, thus suppressing the...

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Literature Corpus work: 285f6653-06b0-53c6-9b95-3c1447ebd20e
DOI: 10.1101/2025.04.03.646615

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