Article

Asymmetric inheritance of centrosomes maintains stem cell properties in human neural progenitor cells

2022-09-22

Abstract excerpt

During human forebrain development, neural progenitor cells (NPCs) in the ventricular zone (VZ) undergo asymmetric cell divisions to produce a self-renewed progenitor cell, maintaining the potential to go through additional rounds of cell divisions, and differentiating daughter cells, populating the developing cortex. Previous work in the embryonic rodent brain suggested that the preferential inheritance of the pr...

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Literature Corpus work: 4b24c0b0-78ac-54d9-8609-8a795cdd05be
DOI: 10.1101/2022.09.20.508710

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