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Article

Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisions

1 Sept 2011

Abstract excerpt

Malignant gliomas contain a population of self-renewing tumorigenic stem-like cells; however, it remains unclear how these glioma stem cells (GSCs) self-renew or generate cellular diversity at the single-cell level. Asymmetric cell division is a proposed mechanism to maintain cancer stem cells, yet the modes of cell division that GSCs utilize remain undetermined. Here, we used single-cell analyses to evaluate the...

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PMID: 21881602
DOI: 10.1038/cddis.2011.80

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