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Polymorphisms in rs2069845 are associated with IL-6 and soluble IL-6 receptor levels during total joint replacement

2024-10-21

Abstract excerpt

As the number of patients undergoing total joint replacement (TJR) surgery increases, so does the number of revision surgeries. One driver of implant failure and subsequent revision surgery is peri-implant osteolysis, which is driven by inflammation-mediated bone loss. IL-6 is an inflammatory marker that is elevated during the peri-operative period. Early elevations in IL-6 levels have been linked to osteolysis de...

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Literature Corpus work
4b18a78f-d6dd-5e08-b4cc-8ed9024d682e
DOI
10.1101/2024.10.18.619020
Open publication

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Polymorphisms in rs2069845 are associated with IL-6 and soluble IL-6 receptor levels during total joint replacementDOI 10.1101/2024.10.18.619020
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