The IL-6 rs12700386 polymorphism is associated with an increased risk of developing osteoarthritis in the knee in the Chinese Han population: a case-control study

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> This case-control study aims to examine the association between the Interleukin-6 (IL-6) rs12700386 polymorphism and the increased risk of developing osteoarthritis (OA) in the knee in the Chinese Han population.<bold>Methods:</bold> We extracted DNA from 763 subjects (352 OA patients and 411 healthy controls). The relative expression levels of IL-6 in blood sam...

Topics

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• Asian People
• Case-Control Studies
• China
• Gene Frequency
• Interleukin-6
• Osteoarthritis, Knee
• Polymerase Chain Reaction
• Polymorphism, Restriction Fragment Length

Identifiers and source

Literature Corpus work

ebff4695-7b5b-5952-a7e9-1ed9f54d6e8c

DOI

10.21203/rs.3.rs-32756/v4