Article
A pilot study of single nucleotide polymorphisms in the interleukin-6 receptor and their effects on pre- and post-transplant serum mediator level and outcome after allogeneic stem cell transplantation.
Clinical and experimental immunology - 1 Jul 2018
Tvedt T H A, Hovland R, Tsykunova G, Ahmed A B, Gedde-Dahl T, Bruserud Ø
Abstract excerpt
Interleukin (IL)-6 is an important regulator of immunity and inflammation in many diseases. Single nucleotide polymorphisms (SNPs) in the IL-6 gene influence outcome after allogeneic stem cell transplantation (ASCT), but the possible importance of SNPs in the IL-6 receptor has not been examined. We therefore investigated whether SNPs in the IL-6R gene influenced biochemical characteristics and clinical outcomes...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.