Article
Interleukin-6 gene polymorphism and risk of osteoarthritis of the hip: a case-control study.
Osteoarthritis and cartilage - 1 Nov 2005
Pola E, Papaleo P, Pola R, Gaetani E, Tamburelli F C, Aulisa L, Logroscino C A
Abstract excerpt
OBJECTIVES: Osteoarthritis (OA) is considered a polygenic disease controlled by the expression of genetic factors. Genes encoding for cytokines have been associated with susceptibility for joint OA and interleukin (IL)-6 gene is also supposed to be involved in the cartilage degradation process. In this case-control study, we evaluated for the first time whether the risk of hip OA might be influenced by the -174...
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