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Association of interleukin-6 gene polymorphism (rs1800796) with severity and functional status of osteoarthritis in elderly individuals.

Cytokine - 1 Oct 2015

Fernandes Marcos T P, Fernandes Karen B P, Marquez Audrey S, Cólus Ilce M S, Souza Marilesia F, Santos João Paulo M, Poli-Frederico Regina C

Abstract excerpt

Osteoarthritis (OA) is the most prevalent disease of the musculoskeletal system and it has an important genetic component. Despite several reports have shown the involvement of pro-inflammatory cytokine such as interleukin-1β and TNF-α, the role of interleukin-6 (IL-6) in osteoarthritis is still unclear. Thus, this study aimed to analyze the relationship between the single nucleotide polymorphism in the portion...

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PMID: 26233477
DOI: 10.1016/j.cyto.2015.07.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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