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LDL Receptor–Related Protein-1

12 Oct 2013

Abstract excerpt

Low-density lipoprotein receptor-related protein-1 (LRP1) is an endocytic receptor for numerous proteins that are both structurally and functionally diverse. In some cell types, LRP1-mediated endocytosis is coupled to activation of cell signaling. LRP1 also regulates the composition of the plasma membrane and may, thereby, indirectly regulate the activity of other cell-signaling receptors. Given the scope of LRP1...

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PMID: 24128688
DOI: 10.1016/j.ajpath.2013.08.029

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