Article

A neurovascular progenitor sits at the nexus of glioblastoma lineage trajectories

2024-07-24

Abstract excerpt

Glioblastoma (GBM) exhibits developmental programs and marked cellular heterogeneity, yet how these features are organized into connected lineage hierarchies remains unclear. Here we identify a rare tumor-intrinsic population, termed the neurovascular progenitor (NVP), that occupies an intermediate position between the major GBM organizational axes. NVP cells co-express neural progenitor and perivascular transcrip...

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Literature Corpus work: 4aa0175c-d160-59ee-8c24-2fc2a4b966ca
DOI: 10.1101/2024.07.24.604840

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