Article

Single-cell RNA-seq reveals that glioblastoma recapitulates normal brain development

2018-10-22

Abstract excerpt

<h4>Summary</h4> Cancer stem cells are critical for cancer initiation, development, and resistance to treatments. Our understanding of these processes, and how they relate to glioblastoma heterogeneity, is limited. To overcome these limitations, we performed single-cell RNA-sequencing on 38 296 glioblastoma cells and 22 637 normal human fetal brain cells. Using an unbiased approach, we mapped the lineage hierarch...

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Literature Corpus work: a22f778a-8c00-5a23-aba0-10d760591fc7
DOI: 10.1101/449439

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