Article

Single-cell morphology encodes functional subtypes of senescence in aging human dermal fibroblasts

2024-05-14

Abstract excerpt

<h4>ABSTRACT</h4> Cellular senescence is an established driver of aging, exhibiting context-dependent phenotypes across multiple biological length-scales. Despite its mechanistic importance, profiling senescence within cell populations is challenging. This is in part due to the limitations of current biomarkers to robustly identify senescent cells across biological settings, and the heterogeneous, non-binary phen...

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Literature Corpus work: 3d6daa59-2b11-5a95-a4a8-d23e7a443372
DOI: 10.1101/2024.05.10.593637

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