Article

A non-genetic model of vascular shunts informs on the cellular mechanisms of formation and resolution of arteriovenous malformations

2023-08-22

Abstract excerpt

Arteriovenous malformations (AVMs), a disorder characterized by direct shunts between arteries and veins, are associated with genetic mutations. However, the mechanisms leading to the transformation of a capillary into a shunt remain unclear and how shunts can be reverted into capillaries is poorly understood. Here, we report that oxygen-induced retinopathy (OIR) protocol leads to the consistent and stereotypical...

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Literature Corpus work: 4a65d8e1-0dd6-5672-a03b-c94cc1076c23
DOI: 10.1101/2023.08.21.554159

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