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Article

A non-genetic model of vascular shunts informs on the cellular mechanisms of formation and resolution of arteriovenous malformations.

Cardiovascular research - 4 Dec 2024

Ouarné Marie, Pena Andreia, Ramalho Daniela, Conchinha Nadine V, Costa Tiago, Enjalbert Romain, Figueiredo Ana M, Saraiva Marta Pimentel, Carvalho Yulia, Bernabeu Miguel O, Henao Misikova Lenka, Oh S Paul, Franco Cláudio A

Abstract excerpt

AIMS: Arteriovenous malformations (AVMs), a disorder characterized by direct shunts between arteries and veins, are associated with genetic mutations. However, the mechanisms leading to AV shunt formation and how shunts can be reverted are poorly understood. METHODS AND RESULTS: Here, we report that oxygen-induced retinopathy (OIR) protocol leads to the consistent and stereotypical formation of AV shunts in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39308243
DOI: 10.1093/cvr/cvae160
PMCID: PMC11629978

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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