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Article

RhoA activation-mediated vascular permeability in capillary malformation-arteriovenous malformation syndrome: a hypothesis.

Drug discovery today - 1 Aug 2021

Eisa-Beygi Shahram, Vo Nghia Jack, Link Brian A

Abstract excerpt

Capillary malformation-arteriovenous malformation (CM-AVM) syndrome is a class of capillary anomalies that are associated with arteriovenous malformations and arteriovenous fistulas, which carry a risk of hemorrhages. There are no broadly effective pharmacological therapies currently available. Most CM-AVMs are associated with a loss of RASA1, resulting in constitutive activation of RAS signaling. However,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 33358701
DOI: 10.1016/j.drudis.2020.12.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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