Article

Enzyme-mediated alkynylation enables transcriptome-wide identification of pseudouridine modifications

2023-06-18

Abstract excerpt

Pseudouridine (Ψ) is one of the most abundant chemical modifications that exists in various types of RNA species and is known to play important roles in RNA function. The advances in studies of Ψ in less abundant messenger RNA species have been hindered by a lack of suitable methods to precisely and sensitively map their distributions. Here we show that a methyltransferase from Methanocaldococcus jannaschii can l...

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Literature Corpus work: a85b932e-ef0b-5b75-bb24-85f619458325
DOI: 10.1101/2023.06.18.545436

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