Article

Genetic Determinants of Heart Failure Susceptibility and Response in the Collaborative Cross Mouse Population

2025-10-08

Abstract excerpt

Genetic variation and lived experiences shape how our hearts respond to chronic stress. The specific genetic mechanisms which underly cardiac remodeling, however, are still unclear, due in part to the challenge of accounting for environmental effects in human population studies. To overcome this challenge, we used the Collaborative Cross (CC) mouse population to investigate heritable susceptibility to cardiovascul...

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Literature Corpus work: 49e9849a-f691-5a2e-9aaa-849daefe6753
DOI: 10.1101/2025.10.07.681046

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