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Genetic architecture of heart mitochondrial proteome influencing cardiac hypertrophy

19 May 2023

Abstract excerpt

Mitochondria play an important role in both normal heart function and disease etiology. We report analysis of common genetic variations contributing to mitochondrial and heart functions using an integrative proteomics approach in a panel of inbred mouse strains called the Hybrid Mouse Diversity Panel (HMDP). We performed a whole heart proteome study in the HMDP (72 strains, n=2-3 mice) and retrieved 848...

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Adipose Tissue and Metabolism
ATP Synthase and ATPases Research
Mitochondrial Function and Pathology

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37276142
DOI: 10.7554/elife.82619

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