Article

The trimeric structures of the extracellular domains of FAM171A1 and FAM171A2 neuronal proteins belong to a novel structural superfamily

2025-09-19

Abstract excerpt

<h4>ABSTRACT</h4> Cell surface molecules play fundamental roles in cell-cell communication, attraction, or repulsion, and when expressed in neurons they are often implicated in neurological disorders. FAM171 is a family of three type-I transmembrane domain cell surface proteins (FAM171A1, FAM171A2, and FAM171B) expressed in several human tissues and especially enriched in the brain. Recent findings suggest that F...

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Literature Corpus work: 4957cf75-3daf-5e22-81ca-330efe522e76
DOI: 10.1101/2025.09.18.675241

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