Article

FAM162A is Crucial for Mitochondrial Structure, Dynamics, and Bioenergetics, Driving Cellular Protection and Longevity

2024-12-26

Abstract excerpt

<h4>Introduction</h4> FAM162A is a mitochondrial protein evolutionarily conserved across taxa and ubiquitously expressed in various tissues. It is known for its role in hypoxia-induced apoptosis. However, paradoxically, FAM162A is overexpressed in cancer, where its pro-apoptotic function seems overridden, suggesting an alternative role associated with mitochondrial function and cell survival. Additionally, its pr...

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Literature Corpus work: 3900f782-2e35-5e1c-836a-86606675219a
DOI: 10.1101/2024.12.26.630390

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