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Article

Transduction of the human gene FAM8A1 by endogenous retrovirus during primate evolution.

Genomics - 1 Nov 2001

Jamain S, Girondot M, Leroy P, Clergue M, Quach H, Fellous M, Bourgeron T

Abstract excerpt

Capture of cellular mRNA by mobile elements has been an evolutionary catalyst for the spread of genes and a cause of cancer development. Here we present evidence that an orphan gene, FAM8A1 (family with sequence similarity 8), was captured by a retrovirus, followed by multiple retrotransposition events, during primate evolution between 45 and 58 million years ago. This represents the first record of cellular mRNA...

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Identifiers

PMID: 11707071
DOI: 10.1006/geno.2001.6642

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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