Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The FAM171A2 gene is a key regulator of progranulin expression and modifies the risk of multiple neurodegenerative diseases

21 Oct 2020

Abstract excerpt

The FAM171A2 gene is a key regulator of progranulin expression and modifies the risk of multiple neurodegenerative diseases.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Amyotrophic Lateral Sclerosis Research
Share to Parkinson's Disease Mechanisms and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33087363
DOI: 10.1126/sciadv.abb3063

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The FAM171A2 gene is a key regulator of progranulin expression and modifies the risk of multiple neurodegenerative diseasesPMID 33087363Read ↗

A novel deletion in progranulin gene is associated with FTDP-17 and CBSSemantic proximity Read ↗

Progranulin as a therapeutic target in neurodegenerative diseases.Semantic proximity Read ↗

Genetic Regulation of Neuronal Progranulin Reveals a Critical Role for the Autophagy-Lysosome PathwaySemantic proximity Read ↗

Recent Insights into the Involvement of Progranulin in Frontotemporal DementiaSemantic proximity Read ↗

Progranulinopathy: A diverse realm of disorders linked to progranulin imbalancesSemantic proximity Read ↗

Association of progranulin polymorphism rs5848 with neurodegenerative diseases: a meta-analysis.Semantic proximity Read ↗

Progranulin polymorphism rs5848 is associated with increased risk of Alzheimer's disease.Semantic proximity Read ↗

Human genetics as a tool to identify progranulin regulators.Semantic proximity Read ↗

The trimeric structures of the extracellular domains of FAM171A1 and FAM171A2 neuronal proteins belong to a novel structural superfamilySemantic proximity Read ↗

Progranulin: A conductor of receptors orchestra, a chaperone of lysosomal enzymes and a therapeutic target for multiple diseasesSemantic proximity Read ↗

Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17.Semantic proximity Read ↗

Structure, function, and mechanism of progranulin; the brain and beyond.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.