Article

Towards identifying subnetworks from FBF binding landscapes in <i>Caenorhabditis</i> spermatogenic or oogenic germlines

2018-09-20

Abstract excerpt

Metazoan PUF (Pumilio and FBF) RNA-binding proteins regulate various biological processes, but a common theme across phylogeny is stem cell regulation. In Caenorhabditis elegans , FBF ( fem-3 Binding Factor) maintains germline stem cells regardless of which gamete is made, but FBF also functions in the process of spermatogenesis. We have begun to “disentangle” these biological roles by asking which FBF targets a...

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Literature Corpus work: 492f8267-a5f4-5631-abea-768b45ab83de
DOI: 10.1101/422584

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