Article
GLS-1, a novel P granule component, modulates a network of conserved RNA regulators to influence germ cell fate decisions.
PLoS genetics - 1 May 2009
Rybarska Agata, Harterink Martin, Jedamzik Britta, Kupinski Adam P, Schmid Mark, Eckmann Christian R
Abstract excerpt
Post-transcriptional regulatory mechanisms are widely used to influence cell fate decisions in germ cells, early embryos, and neurons. Many conserved cytoplasmic RNA regulatory proteins associate with each other and assemble on target mRNAs, forming ribonucleoprotein (RNP) complexes, to control the mRNAs translational output. How these RNA regulatory networks are orchestrated during development to regulate cell...
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