Article

An RNA binding polymer specifies nematode sperm fate

2016-11-21

Abstract excerpt

Metazoan germ cells develop as sperm or oocytes, depending on chromosomal sex, extrinsic signaling from somatic tissue and intrinsic factors within the germ cells. Gamete fate regulatory networks have been analyzed in nematodes, flies and mammals, but only in C. elegans have terminal intrinsic regulators been identified, which include a Tob/BTG protein family member, FOG-3. Canonical Tob/BTG proteins function as m...

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Literature Corpus work: c738a568-dd5d-5a7c-b0fa-d87f21540ad6
DOI: 10.1101/088914

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