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COP9 signalosome component CSN-5 stabilizes PUF proteins FBF-1 and FBF-2 in <i>Caenorhabditis elegans</i> germline stem cells

2022-06-26

Abstract excerpt

RNA-binding proteins FBF-1 and FBF-2 (FBFs) are required for germline stem cell maintenance and the sperm/oocyte switch in Caenorhabditis elegans , though the mechanisms controlling FBF protein levels remain unknown. We identified an interaction between both FBFs and CSN-5, a component of the COP9 (constitutive photomorphogenesis 9) signalosome. Here, we find that the MPN (Mpr1/Pad1 N terminal) metalloprotease do...

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Identifiers and source

Literature Corpus work
13285217-d7d4-57ee-a53e-25d06355b6af
DOI
10.1101/2022.06.22.497213
Open publication

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COP9 signalosome component CSN-5 stabilizes PUF proteins FBF-1 and FBF-2 in <i>Caenorhabditis elegans</i> germline stem cellsDOI 10.1101/2022.06.22.497213
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