Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Puf RNA-binding proteins FBF-1 and FBF-2 inhibit the expression of synaptonemal complex proteins in germline stem cells.

Development (Cambridge, England) - 1 Jun 2010

Merritt Christopher, Seydoux Geraldine

Abstract excerpt

FBF-1 and FBF-2 (collectively FBF) are two nearly identical Puf-domain RNA-binding proteins that regulate the switch from mitosis to meiosis in the C. elegans germline. In germline stem cells, FBF prevents premature meiotic entry by inhibiting the expression of meiotic regulators, such as the RNA-binding protein GLD-1. Here, we demonstrate that FBF also directly inhibits the expression of structural components of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Caenorhabditis elegans Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Silencing

Share to Germ Cells

Share to Meiosis

Share to Mitosis

Share to RNA, Helminth

Share to Synaptonemal Complex

Source

Open in PubMed Open full text

Identifiers

PMID: 20431119
DOI: 10.1242/dev.050799
PMCID: PMC2867315

Genes

SYP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Puf RNA-binding proteins FBF-1 and FBF-2 inhibit the expression of synaptonemal complex proteins in germline stem cells.PMID 20431119Read ↗

A conserved RNA-binding protein controls germline stem cells in Caenorhabditis elegans.Semantic proximity Read ↗

LincRNAs enable germ cells differentiation by promoting PUF proteins condensationSemantic proximity Read ↗

Towards identifying subnetworks from FBF binding landscapes in <i>Caenorhabditis</i> spermatogenic or oogenic germlinesSemantic proximity Read ↗

C. elegans RNA-binding proteins PUF-8 and MEX-3 function redundantly to promote germline stem cell mitosisSemantic proximity Read ↗

Controls of Germline Stem Cells, Entry into Meiosis, and the Sperm/Oocyte Decision in<i>Caenorhabditis elegans</i>Semantic proximity Read ↗

Regulation of the mitosis/meiosis decision in the <i>Caenorhabditis elegans</i> germlineSemantic proximity Read ↗

The PUF RNA-binding protein, FBF-2, maintains stem cells without binding to RNA.Semantic proximity Read ↗

COP9 signalosome component CSN-5 stabilizes PUF proteins FBF-1 and FBF-2 in <i>Caenorhabditis elegans</i> germline stem cellsSemantic proximity Read ↗

Splicing Machinery Facilitates Post-Transcriptional Regulation by FBFs and Other RNA-Binding Proteins in Caenorhabditis elegans Germline.Semantic proximity Read ↗

Redundant control of the Caenorhabditis elegans sperm/oocyte switch by PUF-8 and FBF-1, two distinct PUF RNA-binding proteins.Semantic proximity Read ↗

Caenorhabditis elegans SWI/SNF subunits control sequential developmental stages in the somatic gonad.Semantic proximity Read ↗

Cyclin E and Cdk2 Control GLD-1, the Mitosis/Meiosis Decision, and Germline Stem Cells in Caenorhabditis elegansSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.