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Article

Redundant control of the Caenorhabditis elegans sperm/oocyte switch by PUF-8 and FBF-1, two distinct PUF RNA-binding proteins.

Proceedings of the National Academy of Sciences of the United States of America - 2 Aug 2005

Bachorik Jennifer L, Kimble Judith

Abstract excerpt

PUF proteins control both growth and differentiation in the C. elegans germ line. These conserved RNA-binding proteins inhibit expression of target mRNAs, either by repressing translation or promoting degradation. Previous studies showed that PUF-8, a PUF protein with striking similarity to human Pumilio, prevents return of primary spermatocytes to the mitotic cell cycle [Subramaniam, K. & Seydoux, G. (2003)...

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Identifiers

PMID: 16037210
DOI: 10.1073/pnas.0504593102
PMCID: PMC1182444

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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