Article

A rapid platform for 3D patient-derived cutaneous neurofibroma organoid establishment and screening

2022-11-07

Abstract excerpt

Localized cutaneous neurofibromas (cNFs) are benign tumors that arise in the dermis of patients affected by Neurofibromatosis Type 1 syndrome (NF1). cNFs are fundamentally benign lesions: they do not undergo malignant transformation or metastasize. Nevertheless, in NF1 patients, they can cover a significant proportion of the body, with some individuals developing hundreds to thousands of lesions. cNFs can cause pa...

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Literature Corpus work: 3d11afc9-ed89-5425-9aa5-271e947a55a0
DOI: 10.1101/2022.11.07.515469

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