Article
Dynamic Clonal Hematopoiesis and Functional T-cell Immunity in a Super-centenarian
2019-10-01
Abstract excerpt
The aged hematopoietic system is characterized by decreased immuno-competence and by a reduced number of hematopoietic stem cells (HSCs) that actively generates new blood cell (age-related clonal hematopoiesis, ARCH). While both aspects are commonly associated with an increased risk of aging-related diseases, it is currently unknown to what extent these aspects co-occur during exceptional longevity. Here, we inves...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 490720f5-2b1a-5e0e-bcc5-3c9d7157ede9
- DOI
- 10.1101/788752