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[Aging and clonal hematopoesis.]

Advances in gerontology = Uspekhi gerontologii - 1 Jan 2024

Bogdanov A N, Voloshin S V, Kunevich E O, Mikhaleva M A

Abstract excerpt

The number of somatic mutations among all tissues increases along with age. This process was well-studied in hematopoietic stem cells (HSCs). Some mutations lead to a proliferative advantage and expansion of HSCs to form a dominant clone. Clonal hematopoiesis is general in the elderly population. Clonal hematopoiesis of indeterminate potential (CHIP) is a more common phenomenon in the elderly and is defined as...

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PMID: 39139119

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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