Article

Prospective analysis of incident disease among individuals of diverse ancestries using genetic and conventional risk factors

2023-10-24

Abstract excerpt

<h4>Background</h4> Human genetics provides opportunities for enhancing disease prediction through polygenic risk scores (PRS). <h4>Method</h4> We used a dataset from 23andMe (6.77M European, 1.30M Latine, and 0.45M African American individuals). Using cross-sectional data for PRS construction and a prospective cohort for evaluation, we estimated PRS-associated cumulative incidences after one year of follow-up f...

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Literature Corpus work: 48e4da9d-a4c8-5062-a961-76633d7b69d1
DOI: 10.1101/2023.10.23.23297414

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