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Article

Uncovering the heritable components of multimorbidities and disease trajectories using a nationwide cohort.

Nature communications - 28 Aug 2024

Westergaard David, Jørgensen Frederik Hytting, Waaben Jens, Jung Alexander Wolfgang, Lademann Mette, Hansen Thomas Folkmann, Cremers Jolien, Ostrowski Sisse Rye, Pedersen Ole Birger Vesterager, Reguant Roc, Jørgensen Isabella Friis, Fitzgerald Tom, Birney Ewan, Banasik Karina, Mortensen Laust, Brunak Søren

Abstract excerpt

Quantifying the contribution of genetics and environmental effects on disease initiation and progression, as well as the shared genetics of different diseases, is vital for the understanding of the disease etiology of multimorbidities. In this study, we leverage nationwide Danish registries to provide a granular atlas of the genetic origin of disease phenotypes for a cohort of all Danes 1978-2018 with partially...

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PMID: 39198472
DOI: 10.1038/s41467-024-51795-8
PMCID: PMC11358290

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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