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The alternative oxidase reconfigures the larval mitochondrial electron transport system to accelerate growth and development in <i>Drosophila melanogaster</i>

2025-02-23

Abstract excerpt

The alternative oxidase (AOX) is naturally present in the mitochondrial electron transfer system (ETS) of many organisms but absent in vertebrates and most insects. AOX oxidizes coenzyme Q and reduces O 2 in H 2 O, partially replacing the ETS cytochrome c segment and alleviating the oxidative stress caused by ETS overload. As successfully demonstrated in animal models, AOX shows potential in mitigating mitochond...

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Identifiers and source

Literature Corpus work
4895048a-35f8-5897-b80a-29d63f7ee3ff
DOI
10.1101/2025.02.20.639223
Open publication

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The alternative oxidase reconfigures the larval mitochondrial electron transport system to accelerate growth and development in <i>Drosophila melanogaster</i>DOI 10.1101/2025.02.20.639223
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