Article

Astaxanthin extends lifespan via altered biogenesis of the mitochondrial respiratory chain complex III

2019-07-10

Abstract excerpt

Astaxanthin is a keto -carotenoid produced in some bacteria and algae, which has very important industrial applications (i.e., in cosmetics, coloring additive in aquaculture and as a dietary supplement for human). Here, we analyzed the molecular basis of Astaxanthin-mediated prolongevity in the model organism, Caenorhabditis elegans . The increased lifespan effects of Astaxanthin are restricted in C. elegans to...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7081a2ed-597b-5e27-b634-24a6a72c87d4
DOI: 10.1101/698001

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Astaxanthin extends lifespan via altered biogenesis of the mitochondrial respiratory chain complex IIIDOI 10.1101/698001Read

Succinate dehydrogenase upregulation destabilize complex I and limits the lifespan of gas-1 mutant.Semantic proximity Read

Astaxanthin Induces Transcriptomic Responses Associated with Lifespan Extension in Caenorhabditis elegansSemantic proximity Read

DAF-16 acts as the "hub" of astaxanthin's anti-aging mechanism to improve aging-related physiological functions in Caenorhabditis elegans.Semantic proximity Read

Supplemental cellular protection by a carotenoid extends lifespan via Ins/IGF-1 signaling in Caenorhabditis elegans.Semantic proximity Read

Gastrodin extends the lifespan of Caenorhabditis elegans via the DAF-16/FOXO signaling pathway and autophagySemantic proximity Read

Raspberry extract promoted longevity and stress tolerance via the insulin/IGF signaling pathway and DAF-16 in Caenorhabditis elegansSemantic proximity Read

Autophagy Plays a Role in the Prolongation of the Life Span of Caenorhabditis elegans by AstaxanthinSemantic proximity Read

Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans.Semantic proximity Read

N-acetylcysteine and vitamin E rescue animal longevity and cellular oxidative stress in pre-clinical models of mitochondrial complex I disease.Semantic proximity Read

Effects of the mitochondrial respiratory chain on longevity in C. elegans.Semantic proximity Read

Trigonelline Extends the Lifespan of C. Elegans and Delays the Progression of Age‐Related Diseases by Activating AMPK, DAF‐16, and HSF‐1Semantic proximity Read

Molecular mechanism of culinary herb Artemisia argyi in promoting lifespan and stress toleranceSemantic proximity Read