Article
The alternative oxidase AOX does not rescue the phenotype of tko25t mutant flies.
G3 (Bethesda, Md.) - 21 Aug 2014
Kemppainen Kia K, Kemppainen Esko, Jacobs Howard T
Abstract excerpt
A point mutation [technical knockout(25t) (tko(25t))] in the Drosophila gene coding for mitoribosomal protein S12 generates a phenotype of developmental delay and bang sensitivity. tko(25t) has been intensively studied as an animal model for human mitochondrial diseases associated with deficiency...
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