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Resident and recruited macrophages differentially contribute to cardiac healing after myocardial ischemia

2024-05-22

Abstract excerpt

Cardiac macrophages are heterogenous in phenotype and functions, which has been associated with differences in their ontogeny. Despite extensive research, our understanding of the precise role of different subsets of macrophages in ischemia/reperfusion (I/R) injury remains incomplete. We here investigated macrophage lineages and ablated tissue macrophages in homeostasis and after I/R injury in a CSF1R-dependent ma...

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Literature Corpus work
3d251e27-d2ff-57d4-b47d-e5325ab9700d
DOI
10.7554/elife.89377.4
Open publication

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Resident and recruited macrophages differentially contribute to cardiac healing after myocardial ischemiaDOI 10.7554/elife.89377.4
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