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The Wnt1-Cre2 transgene causes aberrant recombination in non-neural crest cell types

2024-11-06

Abstract excerpt

The Wnt1-Cre2 driver, designed to address the effect of Wnt1 overactivation in the ventral neural tube in the original Wnt1-Cre line, was recently shown to have ectopic expression in the male germline. When crossed with a reporter mouse, we observed fluorescent protein expression in non-neural-crest cell types in the gut. Here, we characterize the pattern of Cre-mediated recombination in the Wnt1-Cre2 driver using...

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Literature Corpus work
48488342-1aa2-5e68-ac0e-fc41f7b11e78
DOI
10.1101/2024.11.06.622365
Open publication

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The Wnt1-Cre2 transgene causes aberrant recombination in non-neural crest cell typesDOI 10.1101/2024.11.06.622365
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