Article
Generation and characterization of a tamoxifen-inducible Eomes(CreER) mouse line.
Genesis (New York, N.Y. : 2000) - 1 Oct 2013
Pimeisl Inga-Marie, Tanriver Yakup, Daza Ray A, Vauti Franz, Hevner Robert F, Arnold Hans-Henning, Arnold Sebastian J
Abstract excerpt
Transgenic mouse lines expressing inducible forms of Cre-recombinase in a tissue-specific manner are powerful genetic tools for studying aspects of development and various processes in the adult. The T-box transcription factor eomesodermin (Eomes) plays critical roles for maintenance and differentiation of different pools of stem and progenitor cells from early embryonic stages to adulthood. These include...
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