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Article

Wnt-reporter expression pattern in the mouse intestine during homeostasis

1 Dec 2008

Abstract excerpt

BACKGROUND: The canonical Wnt signaling pathway is a known regulator of cell proliferation during development and maintenance of the intestinal epithelium. Perturbations in this pathway lead to aberrant epithelial proliferation and intestinal cancer. In the mature intestine, proliferation is confined to the relatively quiescent stem cells and the rapidly cycling transient-amplifying cells in the intestinal...

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PMID: 19055726
DOI: 10.1186/1471-230x-8-57

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