Article

A subpopulation of Talin 1 resides in the nucleus and regulates gene expression

2022-03-15

Abstract excerpt

Talin 1 (TLN1) is best known for its role at focal adhesions, where it activates β-integrin receptors and transmits mechanical stimuli to the actin cytoskeleton. Interestingly, the localization of TLN1 is not restricted to the focal adhesions, but its function in other cellular compartments remains poorly understood. By utilizing both biochemical and confocal microscopy analyses, we show that TLN1 localizes to the...

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Literature Corpus work: 480b2523-a750-5cf2-962c-f315cb2cb924
DOI: 10.1101/2022.03.15.484419

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