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Article

Nuclear TAZ expression associates with the triple-negative phenotype in breast cancer.

Endocrine-related cancer - 1 Jun 2015

Díaz-Martín Juan, López-García María Ángeles, Romero-Pérez Laura, Atienza-Amores María Reina, Pecero María Luisa, Castilla María Ángeles, Biscuola Michele, Santón Almudena, Palacios José

Abstract excerpt

The Hippo signaling pathway, a conserved regulator of organ size, has emerged as an important regulatory pathway in cancer. The final transducer effectors of this pathway in mammals are the oncoproteins TAZ and YAP1, which are transcriptional coactivators of target genes involved in cell proliferation and survival. TAZ has been previously reported to play a role in tumorigenesis in breast cancer, but detailed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25870251
DOI: 10.1530/ERC-14-0456

Genes

YAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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