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Impact of SLCO1B3 rs4149117, CYP2C8 rs11572080, and ABCC2 rs17222723 Polymorphisms on Toxicity and Clinical Outcomes in AC-T Treated Breast Cancer Patients in Bangladesh

2026-05-12

Abstract excerpt

<title>Abstract</title> <p>Women receiving doxorubicin, cyclophosphamide, and taxane-based chemotherapy show considerable differences in both benefit and toxicity, and clinical factors alone do not fully explain this variation. Genetic differences in drug transport and metabolism may contribute; however, data from South Asian populations, including those from Bangladesh, are limited. This study evaluates the SLCO...

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Literature Corpus work
47ffd93e-9d21-5ba6-8d99-7066454a6c37
DOI
10.21203/rs.3.rs-8348792/v1
Open publication

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Impact of SLCO1B3 rs4149117, CYP2C8 rs11572080, and ABCC2 rs17222723 Polymorphisms on Toxicity and Clinical Outcomes in AC-T Treated Breast Cancer Patients in BangladeshDOI 10.21203/rs.3.rs-8348792/v1
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